For Researchers
Data and samples to use in reserach.
For Participants
Information to participants; only in Swedish.
For the Public
If you are interested in the outcomes from the research on the cohorts in SIMPLER; only in Swedish.
Swedish Infrastructure for Medical Population-based Life-course and Environmental Research – SIMPLER
SIMPLER is an infrastructure with the purpose of providing national and international researchers with data for research about dietary and lifestyle factors as well as genetics, and how they affect our health, particularly in the latter part of life. The data in the SIMPLER database is collected from samples and questionnaire responses from two cohorts which form the basis of SIMPLER.
SIMPLER's smorgasbord of data and samples are made available for research projects via an application process. Criteria for use of SIMPLER data include an ethical approval from the Swedish Ethical Review Board and clear and relevant research questions. Researchers in academia as well as in the business sector are welcome to apply for a project in SIMPLER.
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SIMPLER's smorgasbord consists of data and samples available for research.
News within SIMPLER
New publication describing SMC and COSM
Warensjö Lemming et al. Eur J Epidemiol. 2026 Oct 12. doi: 10.1007/s10654-026-01455-6. Online ahead of print. PMID: 42862264
Profiling of 17 elements in urine
During the beginning of the autumn SIMPLER received data on 17 elements in urine, both essential and toxic.
Vitamin D and lipids in fat
From 2026 until 2028 fat biopsies will be analyzed for vitamin D and lipids. All samples have been sent to Chalmers Mass Spectrometry Infrastructure at Chalmers University of Technology, where they will undergo extraction and analysis for vitamin D using HP LC-MS. A subset of the extract will be analyzed for lipids at Örebro University using HP GC-MS.
SIMPLER 2029-2034
SIMPLER was included in the invenvtory of research infrastructure of national intererest conducted by the Swedish Research Council 2025-2026. The outcome was positive, and SIMPLER has advanced to the call for grants for reserach infrastructures of national interest, which opens in December 2026.
Partners
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Swedish National Infrastructures
Some Swedish national infrastructures financed by the Swedish Research Council with resources that may be of interest:
Comparative Research Center Sweden, CORS
CORS is a national research infrastructure consortium that incorporates the largest, most influential and most widely used, international and national survey programs in Sweden. These are the European Social Survey (ESS), European Values Study (EVS), International Social Survey Programme (ISSP), Survey of Health, Ageing and Retirement in Europe (SHARE) and the Swedish National Election Studies (SNES). The Swedish Citizen Panel (SCP) at the SOM Institute is also part of CORS. SCP is a research driven webpanel that offers ways of conducting various methodological experiments as well as following individuals or groups over time. The aim of CORS is to enable class-leading comparative survey research, and to contribute to improved policymaking and democratic debate in Sweden.
The National E-infrastructure for Aging Research, NEAR
NEAR promotes and supports aging research by facilitating the use of longitudinal population-based data from various well-known Swedish studies on aging and health. It is based on a collaboration among eight Swedish universities and includes 17 databases linked to registers. Additionally, NEAR collaborates with other national infrastructures such as SIMPLER and CORS. NEAR’s mission is to enable high-quality aging research by providing big health data while maintaining the same quality and richness as in single population-based studies. Moreover, NEAR aims to increase national and international exchange and collaboration and enhance the quality and generalizability of aging research results. NEAR provides a broad range of biomedical, clinical, social, and psychological health data from over 180,000 older adults followed for more than
50 years.
Relations, Work and Health across the life-course – A Research Data Infrastructure, REWHARD
The Swedish Twin Registry (STR) is a national database that collects, stores and shares data on twins for the purpose of research. Project applications are reviewed and approved by STR's expert group. It is possible for researchers to obtain addresses to contact twins themselves or add questions to our ongoing surveys after approval.
The data collection started in the 60s and currently includes 135,000 twins. All twins born in Sweden are invited at the age of <1, 9, 15, 18
and 24. Parents and/or the twins answer online questionnaires and provide DNA samples (the twins). Follow-ups then take place repeatedly during aging.
Data includes zygosity, survey data, measurement of physical activity, genotypes, biomarkers, DNA and serum. Metadata is available at strdata.se.
Swedish Population Databases for Research, SwedPop
Evaluation Through Follow-up, UGU
Evaluation Through Follow-up (UGU) is a longitudinal study that has developed a unique database within the field of educational science. UGU consists of several longitudinal surveys that have been combined into a whole, which together creates a cohort sequential database. The database contains 10 different birth cohorts that are nationally representative samples which make it possible to carry out longitudinal, sequential, and cross-sectional analyses. The data consists of administrative tasks, measures of study prerequisites, survey tasks, study results and cognitive tests. UGU is one of the oldest social science databases in Sweden, the first survey was carried out in 1961.