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Cohorts in SIMPLER

Graphic representation of the collection of data for SIMPLER on a time line

Time line for questionnaires in the cohorts.

A description of the cohorts is published by Harris et al. (2013) "The Swedish mammography cohort and the cohort of Swedish men: study design and characteristics of two population-based longitudinal cohorts" (pdf) Pdf, 353 kB.. Please note that there is an incorrect number in Figure 1 for SMC at "1997, Cohort after exclusions"; it should be 38,984 instead of 39,984.

A more detailed timeline of data collection for both the main cohorts and the subcohorts is available in this excel file Excel, 938 kB..

For a short overview of the cohorts, you may explore this summary Excel, 21 kB. in excel with numbers on respondents and exclusions.

PARTICIPANTS SMC AND COSM

Questionnaire

SMC

COSM

1987

61,433

 

1997

38,984

45,906

2008 Health questionnaire

30,621

29,503

2009 Lifestyle questionnaire

25,332

26,100

2019 Health questionnaire

19,081

18,916

2019 Lifestyle questionnaire

14,923

16,166

Please read our pages for the Questionnaires and the Variable Lists for exact formulations of questions and variables.

 

PARTICIPANTS IN THE CLINICAL COHORTS

 

SMC clinical subcohort Uppsala

SMC clinical subcohort Västerås

COSM clinical subcohort Västerås

COSM clinical subcohort Örebro

Cycle 1

N=5,032, collected

2003–2009

N=2,630, collected
2010–2019

N=4,750, collected
2010–2019

N=602, collection started 2014 and ongoing

Cycle 2

N=1,232, collection started May 2015 and ongoing

Started October 2022

Started October 2022

 

85+, home visit

N=307, collected 2012–2013

 

N=87, collected

2013–2014

 

*Sampling at Karolinska Institutet

 

*N=82, collected 2014

*N=25, collected 2014

 

*Residents in Västmanland or Örebro County at the start of SMC (1987) and COSM (1997) who had moved to and were living in Stockholm at the time of invitation to participate in the clinical subcohort.

 

**NUMBER OF CASES OF DEATH AND DIFFERENT DISEASES AFTER COHORT ENTRY

 

SMC,
1987–2020

COSM,
1997–2020

SUM

Death

30,290

22,101

52,391

Cancer

16,398

13,923

30,321

CVD

42,259

32,203

74,462

IHD

12,387

12,965

25,352

AMI

6,890

7,025

13,915

Stroke

9,223

7,033

16,256

Heart failure

12,055

9,140

21,195

Diabetes

10,116

8,846

18,962

Fracture, all

23,309

10,249

33,558

Hip fracture

7,894

2,840

10,734

Cataract extraction

20,279

11,147

31,426

** The table shows the total number of outcomes. Number of incident cases varies depending on the type of analysis.

CVD, Cardiovascular disease; IHD, Ischemic heart disease; AMI, Acute myocardial infarction

Contact

For questions regarding the infrastructure, cohorts, or the SIMPLER biobank, you are welcome to contact the SIMPLER Office at simpler@surgsci.uu.se.

For questions regarding the precossing of personal data at Uppsala University, please contact the data protection officer. This is easily done through the form available on the university's Data protection policy webpage.