Biorepository

Samples of fasting whole blood, serum, plasma, buffy coat, urine, fat biopsies, and stool have been collected from the clinical subcohorts of women and men. The samples have been collected after over-night fasting. They have been protected from light during collection. Serum and plasma has been aliquoted after cool centrifugation. All the samples are stored in -80°C freezers.

Approximately 40,000 DNA samples (from 8,500 females and 31,500 males) of saliva are available for analysis of DNA from oral microbiota. The biobank also contains approximately 13,000 DNA samples extracted from blood, but due to overlapping collection of saliva and blood the number of DNA samples for unique indivduals is approximately 38,000. DNA is stored in -20°C freezers.

In addition, researchers at Örebro University and Örebro Hospital have been collecting blood samples (whole blood, plasma, and serum) for four years in COSM with incident urological cancer (prostate, kidney, bladder, and penile cancer). Urine is also collected from prostate cancer patients. Samples from approximately 602 incident cancer cases have been collected thus far.